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'Female Viagra' pill approved by US drug agency | |
(35 minutes later) | |
The US Food and Drug Administration (FDA) has approved a libido-enhancing drug for women dubbed the "female Viagra". | The US Food and Drug Administration (FDA) has approved a libido-enhancing drug for women dubbed the "female Viagra". |
Flibanserin, a drug produced by Sprout Pharmaceuticals, recently passed an FDA advisory committee meeting. | Flibanserin, a drug produced by Sprout Pharmaceuticals, recently passed an FDA advisory committee meeting. |
The drug, marketed as Addyi, has been criticised as having marginal benefits. | The drug, marketed as Addyi, has been criticised as having marginal benefits. |
Unlike Viagra, which affects blood flow to the genitals, Addyi is designed to help women regain their sex drive by boosting levels of brain chemicals. | |
Sprout said trials had shown an increase "in the number of satisfying sexual events", although experts suggest the test results were modest. | |
'An unmet need' | 'An unmet need' |
Versions of the pill have been submitted for approval in the past but never passed. | Versions of the pill have been submitted for approval in the past but never passed. |
It was rejected by the FDA twice for lack of effectiveness and side effects like nausea, dizziness and fainting. | It was rejected by the FDA twice for lack of effectiveness and side effects like nausea, dizziness and fainting. |
But an FDA advisory meeting on 4 June concluded by 18 votes to six that it should be approved. | But an FDA advisory meeting on 4 June concluded by 18 votes to six that it should be approved. |
The FDA said strict measures would be put in place to ensure patients were aware of the risks, including a warning not to drink alcohol with the drug. | The FDA said strict measures would be put in place to ensure patients were aware of the risks, including a warning not to drink alcohol with the drug. |
It will be made available through certified health care professionals and pharmacies from October. | It will be made available through certified health care professionals and pharmacies from October. |
What is hypoactive sexual desire disorder (HSDD)? | What is hypoactive sexual desire disorder (HSDD)? |
There will be warnings of the possible side effects, particularly for those with liver ailments, or if taken with certain other medicines, such as types of steroid. | There will be warnings of the possible side effects, particularly for those with liver ailments, or if taken with certain other medicines, such as types of steroid. |
The FDA said the drug's purpose was the "treatment of hypoactive sexual desire disorder (HSDD)". | The FDA said the drug's purpose was the "treatment of hypoactive sexual desire disorder (HSDD)". |
A doctor would have to determine whether a woman seeking the pill was suffering from the disorder - characterised by a lack of desire, causing her distress. | A doctor would have to determine whether a woman seeking the pill was suffering from the disorder - characterised by a lack of desire, causing her distress. |
Currently, there is no drug on the US market approved for treatment of HSDD or another condition, female sexual interest/arousal disorder (FSIAD). | Currently, there is no drug on the US market approved for treatment of HSDD or another condition, female sexual interest/arousal disorder (FSIAD). |
"This condition is clearly an area of unmet medical need," the FDA said. | "This condition is clearly an area of unmet medical need," the FDA said. |
The dose would be daily, with some doctors cautioning it would need to be taken for weeks for any benefit to be seen. | The dose would be daily, with some doctors cautioning it would need to be taken for weeks for any benefit to be seen. |
The FDA said the treatment should be stopped after eight weeks if there was no improvement. | The FDA said the treatment should be stopped after eight weeks if there was no improvement. |
Sprout only has 25 employees. Large pharmaceutical companies like Pfizer, Bayer and Proctor & Gamble have all studied female sexual desire disorder treatment but abandoned plans to pursue it. | Sprout only has 25 employees. Large pharmaceutical companies like Pfizer, Bayer and Proctor & Gamble have all studied female sexual desire disorder treatment but abandoned plans to pursue it. |
Sprout's CEO, Cindy Whitehead, told Associated Press it would promote Addyi carefully. | Sprout's CEO, Cindy Whitehead, told Associated Press it would promote Addyi carefully. |
"We would never want a patient who's not going to see a benefit to take it and tell everyone it doesn't work," she said. | "We would never want a patient who's not going to see a benefit to take it and tell everyone it doesn't work," she said. |
Lobbying by Sprout Pharmaceuticals was backed by the women's rights group Even the Score, which has accused the FDA of gender bias by approving a number of drugs treating erectile dysfunction in men without passing an equivalent for women. | Lobbying by Sprout Pharmaceuticals was backed by the women's rights group Even the Score, which has accused the FDA of gender bias by approving a number of drugs treating erectile dysfunction in men without passing an equivalent for women. |
Originally the drug was produced by German company Boehringer Ingelheim. Sprout bought the drug from that company after it was turned down by the FDA. | Originally the drug was produced by German company Boehringer Ingelheim. Sprout bought the drug from that company after it was turned down by the FDA. |
Are you affected by the issues in this story? How would a 'Female Viagra' drug help you? You can share your experiences by emailing haveyoursay@bbc.co.uk. | Are you affected by the issues in this story? How would a 'Female Viagra' drug help you? You can share your experiences by emailing haveyoursay@bbc.co.uk. |
Please include a telephone number if you are willing to be contacted by a BBC journalist. | Please include a telephone number if you are willing to be contacted by a BBC journalist. |