This article is from the source 'bbc' and was first published or seen on . It will not be checked again for changes.
You can find the current article at its original source at http://news.bbc.co.uk/go/rss/-/1/hi/sci/tech/7279088.stm
The article has changed 2 times. There is an RSS feed of changes available.
Previous version
1
Next version
Version 0 | Version 1 |
---|---|
'Sea slug' inspires brain implant | |
(about 9 hours later) | |
The response of a startled sea cucumber has inspired a new material that could one day be used to build brain implants for patients with Parkinson's disease. | The response of a startled sea cucumber has inspired a new material that could one day be used to build brain implants for patients with Parkinson's disease. |
The material can rapidly switch from being rigid to flexible and vice versa. | The material can rapidly switch from being rigid to flexible and vice versa. |
Writing in the journal Science, US researchers describe how species of the sea creatures "tense" when threatened. | Writing in the journal Science, US researchers describe how species of the sea creatures "tense" when threatened. |
The new material mimics this ability, and could be used to make advanced brain electrodes which are stiff when implanted, yet supple inside the body. | The new material mimics this ability, and could be used to make advanced brain electrodes which are stiff when implanted, yet supple inside the body. |
Adding water changes the state of the material. | Adding water changes the state of the material. |
See how the material works | See how the material works |
"The water acts as a chemical switch," Dr Christoph Weder, one of the team who developed the material, told the BBC News website. | "The water acts as a chemical switch," Dr Christoph Weder, one of the team who developed the material, told the BBC News website. |
This is important as the brain is around 75% water. | This is important as the brain is around 75% water. |
Chemical change | Chemical change |
The material consists of naturally occurring nanofibres, or "whiskers", carefully embedded in a polymer. | The material consists of naturally occurring nanofibres, or "whiskers", carefully embedded in a polymer. |
The cellulose fibres, each just 25 nanometres (billionths of a metre) in diameter, are harvested from a different sessile sea creature known as a tunicate or sea squirt. | |
The nanofibres are taken from filter-feeding tunicates | The nanofibres are taken from filter-feeding tunicates |
"There are many sources of nanofibres such as cotton or wood [which could be substituted]," said Dr Weder. | |
The structure of the as yet un-named material mimics the skin of sea cucumbers which have collagen nanofibres embedded in a soft connective tissue. | |
"These creatures can reversibly and quickly change the stiffness of their skin," explained Dr Jeffrey Capadona, another member of the team. | "These creatures can reversibly and quickly change the stiffness of their skin," explained Dr Jeffrey Capadona, another member of the team. |
"Normally it is very soft; but for example in response to a threat, the animal can activate its 'body armour' by hardening its dermis." | "Normally it is very soft; but for example in response to a threat, the animal can activate its 'body armour' by hardening its dermis." |
Changes to the stiffness of the sea cucumber's skin are thought to be triggered by chemicals secreted by the animal's nervous system that rearrange the collagen threads. | Changes to the stiffness of the sea cucumber's skin are thought to be triggered by chemicals secreted by the animal's nervous system that rearrange the collagen threads. |
"Our architecture is the same, but the chemistry is different," explained Dr Weder. | "Our architecture is the same, but the chemistry is different," explained Dr Weder. |
In the absence of water, the nanofibres are held together by chemical links known as hydrogen bonds. This gives the material its rigidity. | In the absence of water, the nanofibres are held together by chemical links known as hydrogen bonds. This gives the material its rigidity. |
There is a mechanical mismatch - the electrode is rigid but the brain is more like jello Christoph Weder | There is a mechanical mismatch - the electrode is rigid but the brain is more like jello Christoph Weder |
When exposed to water, the water molecules "competitively bond" with the fibres. | When exposed to water, the water molecules "competitively bond" with the fibres. |
"The water also likes to stick to the cellulose," said Dr Weder. | "The water also likes to stick to the cellulose," said Dr Weder. |
This has an effect of "ungluing" the fibre-to-fibre bonds, and the material becomes about 1,000 times softer, with the consistency of rubber. | This has an effect of "ungluing" the fibre-to-fibre bonds, and the material becomes about 1,000 times softer, with the consistency of rubber. |
When the water evaporates, a network of cross-linked whiskers reforms, stiffening the material. | When the water evaporates, a network of cross-linked whiskers reforms, stiffening the material. |
Brain aid | Brain aid |
This ability to morph could help build therapeutic devices to be implanted into the brains of patients who suffer from Parkinson's disease, stroke or spinal cord injuries. | This ability to morph could help build therapeutic devices to be implanted into the brains of patients who suffer from Parkinson's disease, stroke or spinal cord injuries. |
Enlarge Image | Enlarge Image |
At present, there are a number of research teams hoping to develop "artificial nervous systems" that aim to treat these disorders. | At present, there are a number of research teams hoping to develop "artificial nervous systems" that aim to treat these disorders. |
These systems need to "plug" into nerve cells within the brain - known as cortical neurons - to record electrical activity. | These systems need to "plug" into nerve cells within the brain - known as cortical neurons - to record electrical activity. |
But animal studies have shown that the quality of the brain signals recorded by implanted electrodes often degrades after a few months. | But animal studies have shown that the quality of the brain signals recorded by implanted electrodes often degrades after a few months. |
One hypothesis is that stiff electrodes damage the surrounding brain tissue. | One hypothesis is that stiff electrodes damage the surrounding brain tissue. |
"There is a mechanical mismatch - the electrode is rigid but the brain is more like jello," said Dr Weder. | "There is a mechanical mismatch - the electrode is rigid but the brain is more like jello," said Dr Weder. |
The team believes that an implant built on a substrate of the new material could overcome this problem, by being rigid during implantation, and softening once in the body. | The team believes that an implant built on a substrate of the new material could overcome this problem, by being rigid during implantation, and softening once in the body. |
Dr Weder also has his eye on other applications for the material. Potentially, electricity rather than water could be used to switch its state. | Dr Weder also has his eye on other applications for the material. Potentially, electricity rather than water could be used to switch its state. |
"Smart bullet proof vests, prosthetics - the list goes on and on," he said. | "Smart bullet proof vests, prosthetics - the list goes on and on," he said. |
1. The material consists of carefully arranged nanofibres embedded in polymer. The architecture is based on the skin of a sea cucumber.2. In its natural state, chemical bonds between the nanofibres - known as hydrogen bonds - make the material strong and rigid. 3. When exposed to water, the material swells slightly. The water molecules "unglue" the bonds and the material becomes about 1,000 times softer, with properties that resemble rubber. | 1. The material consists of carefully arranged nanofibres embedded in polymer. The architecture is based on the skin of a sea cucumber.2. In its natural state, chemical bonds between the nanofibres - known as hydrogen bonds - make the material strong and rigid. 3. When exposed to water, the material swells slightly. The water molecules "unglue" the bonds and the material becomes about 1,000 times softer, with properties that resemble rubber. |
Return to text | Return to text |
Previous version
1
Next version