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Three-person IVF baby for infertile couple | Three-person IVF baby for infertile couple |
(about 7 hours later) | |
A baby has been born to a previously infertile couple in Ukraine using a new type of "three-person IVF". | A baby has been born to a previously infertile couple in Ukraine using a new type of "three-person IVF". |
The Times reports that doctors in Kiev used a method called pronuclear transfer in what is a world first. | The Times reports that doctors in Kiev used a method called pronuclear transfer in what is a world first. |
It is not the first baby born with DNA from three parents, however. | It is not the first baby born with DNA from three parents, however. |
The baby, born on 5 January, is thought to be the world's second "modern three-parent baby" - another child was created using a slightly different method in Mexico last year. | The baby, born on 5 January, is thought to be the world's second "modern three-parent baby" - another child was created using a slightly different method in Mexico last year. |
The Kiev team fertilised the mother's egg with her partner's sperm. They then transferred the combined genes into an egg taken from a donor. | |
The child has the genetic identity of the parents, alongside a tiny amount of DNA from the second woman. | |
Tiny bit | Tiny bit |
Doctors developed three-person IVF to help women who are at risk of passing on serious genetic disorders, called mitochondrial disease, to have a healthy child. | Doctors developed three-person IVF to help women who are at risk of passing on serious genetic disorders, called mitochondrial disease, to have a healthy child. |
Eggs from a mother with unhealthy mitochondria and a donor with healthy mitochondria are collected. | Eggs from a mother with unhealthy mitochondria and a donor with healthy mitochondria are collected. |
The Nadiya clinic in Kiev used the technique to treat an infertile couple, not a couple carrying a mitochondrial disease. | The Nadiya clinic in Kiev used the technique to treat an infertile couple, not a couple carrying a mitochondrial disease. |
UK experts said this was "highly experimental". | UK experts said this was "highly experimental". |
Valery Zukin, who led the work, said they had a hunch it would work for the Ukrainian couple who had not been able to conceive with conventional IVF. | Valery Zukin, who led the work, said they had a hunch it would work for the Ukrainian couple who had not been able to conceive with conventional IVF. |
He said he had a second patient - in a similar situation - who is expected to give birth in early March. | He said he had a second patient - in a similar situation - who is expected to give birth in early March. |
The UK has already passed laws to allow three-person IVF for couples with mitochondrial diseases, although no such baby has been born in Britain yet. | The UK has already passed laws to allow three-person IVF for couples with mitochondrial diseases, although no such baby has been born in Britain yet. |
The science is new and controversial and raises ethical questions, including how any child from the technique might feel about having DNA from three people. | The science is new and controversial and raises ethical questions, including how any child from the technique might feel about having DNA from three people. |
Prof Adam Balen, chairman of the British Fertility Society, said: "Pronuclear transfer is highly experimental and has not been properly evaluated or scientifically proven. | Prof Adam Balen, chairman of the British Fertility Society, said: "Pronuclear transfer is highly experimental and has not been properly evaluated or scientifically proven. |
"We would be extremely cautious about adopting this approach to improve IVF outcomes." | "We would be extremely cautious about adopting this approach to improve IVF outcomes." |