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Roman Empire 'raised HIV threat' | Roman Empire 'raised HIV threat' |
(38 minutes later) | |
The spread of the Roman Empire through Europe could help explain why those living in its former colonies are more vulnerable to HIV. | The spread of the Roman Empire through Europe could help explain why those living in its former colonies are more vulnerable to HIV. |
The claim, by French researchers, is that people once ruled by Rome are less likely to have a gene variant which protects against HIV. | The claim, by French researchers, is that people once ruled by Rome are less likely to have a gene variant which protects against HIV. |
This includes England, France, Greece and Spain, New Scientist reports. | This includes England, France, Greece and Spain, New Scientist reports. |
Others argue the difference is linked to a far larger event, such as the spread of bubonic plague or smallpox. | Others argue the difference is linked to a far larger event, such as the spread of bubonic plague or smallpox. |
We're waiting for the big piece of evidence which will solve this Dr Susan ScottLiverpool University | We're waiting for the big piece of evidence which will solve this Dr Susan ScottLiverpool University |
The idea that something carried by the occupying Romans could have a widespread influence on the genes of modern Europeans comes from researchers at the University of Provence. | The idea that something carried by the occupying Romans could have a widespread influence on the genes of modern Europeans comes from researchers at the University of Provence. |
They say that the frequency of the variant corresponds closely with the shifting boundaries of the thousand-year empire. | They say that the frequency of the variant corresponds closely with the shifting boundaries of the thousand-year empire. |
In countries inside the borders of the empire for longer periods, such as Spain, Italy and Greece, the frequency of the CCR5-delta32 gene, which offers some protection against HIV, is between 0% and 6%. | In countries inside the borders of the empire for longer periods, such as Spain, Italy and Greece, the frequency of the CCR5-delta32 gene, which offers some protection against HIV, is between 0% and 6%. |
Countries at the fringe of the empire, such as Germany, and modern England, the rate is between 8% and 11.8%, while in countries never conquered by Rome, the rate is greater than this. | Countries at the fringe of the empire, such as Germany, and modern England, the rate is between 8% and 11.8%, while in countries never conquered by Rome, the rate is greater than this. |
However, the researchers do not believe that the genetic difference is due to Roman soldiers or officials breeding within the local population - history suggests this was not particularly widespread, and that invading and occupying armies could have been drawn not just from Italy but from other parts of the empire. | However, the researchers do not believe that the genetic difference is due to Roman soldiers or officials breeding within the local population - history suggests this was not particularly widespread, and that invading and occupying armies could have been drawn not just from Italy but from other parts of the empire. |
Instead, they say that the Romans may have introduced an unknown disease to which people with the CCR5-Delta32 variant were particularly susceptible. | |
Disease protection | |
However, some researchers believe that infections may have played a role - but in reverse -increasing rather than decreasing the frequency of the variant. | |
Researchers at the University of Liverpool suggested that the variant may have offered protection against pandemics such as the Black Death which swept Europe on a regular basis during and after the Roman era. | |
These, said the Liverpool researchers, were illnesses which may have been lethal to people without the gene variant, raising its frequency from one in 20,000 people to approximately 10% in Northern Europe. | |
Dr Susan Scott, one of the researchers, said that the idea of Roman occupation being the driving force behind this was another theory to be considered. | Dr Susan Scott, one of the researchers, said that the idea of Roman occupation being the driving force behind this was another theory to be considered. |
"We just don't know. This is just another piece of the jigsaw, but we're waiting for the big piece of evidence which will solve this." | "We just don't know. This is just another piece of the jigsaw, but we're waiting for the big piece of evidence which will solve this." |