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| Coronavirus: Children and older adults to take part in vaccine trial | Coronavirus: Children and older adults to take part in vaccine trial |
| (1 day later) | |
| Children and older adults are to be included in the second phase of vaccine trials to protect against coronavirus. | Children and older adults are to be included in the second phase of vaccine trials to protect against coronavirus. |
| The first phase of the University of Oxford trial began in April, involving 1,000 healthy adults aged 55 and under. | The first phase of the University of Oxford trial began in April, involving 1,000 healthy adults aged 55 and under. |
| Now more than 10,200 people - including over 70s and five to 12-year-olds - will be enrolled in the study, to see the effects on their immune system. | Now more than 10,200 people - including over 70s and five to 12-year-olds - will be enrolled in the study, to see the effects on their immune system. |
| Trials of the same vaccine on monkeys appear to have given them some protection against the disease. | Trials of the same vaccine on monkeys appear to have given them some protection against the disease. |
| The animals had less of the virus in their lungs and airways, but it is not certain this finding will translate to people. | The animals had less of the virus in their lungs and airways, but it is not certain this finding will translate to people. |
| The scientists behind the vaccine have previously said they are aiming to have at least a million doses of a coronavirus vaccine by September this year. | The scientists behind the vaccine have previously said they are aiming to have at least a million doses of a coronavirus vaccine by September this year. |
| But the UK government has repeatedly said there are no guarantees - and a vaccine could still be some way off. | But the UK government has repeatedly said there are no guarantees - and a vaccine could still be some way off. |
| And most experts still estimate it will take 12 to 18 months to develop and manufacture a vaccine. | And most experts still estimate it will take 12 to 18 months to develop and manufacture a vaccine. |
| There are more than 100 experimental vaccines against Covid-19 currently being developed worldwide. | |
| Adults in this trial will receive one or two doses of either the new vaccine - ChAdOx1 nCoV-19 - or another licensed vaccine. | Adults in this trial will receive one or two doses of either the new vaccine - ChAdOx1 nCoV-19 - or another licensed vaccine. |
| Researchers will then compare the number of infections in both groups. | Researchers will then compare the number of infections in both groups. |
| This could take between two and to six months, depending on how many people are exposed to the virus. | This could take between two and to six months, depending on how many people are exposed to the virus. |
| The age range of participants has been expanded to include those aged: | The age range of participants has been expanded to include those aged: |
| Sarah Gilbert, professor of vaccinology, at the Jenner Institute, said: "We have had a lot of interest already from people over the age of 55 years who were not eligible to take part in the phase-one study. | Sarah Gilbert, professor of vaccinology, at the Jenner Institute, said: "We have had a lot of interest already from people over the age of 55 years who were not eligible to take part in the phase-one study. |
| "And we will now be able to include older age groups to continue the vaccine assessment. | "And we will now be able to include older age groups to continue the vaccine assessment. |
| "We will also be including more study sites, in different parts of the country." | "We will also be including more study sites, in different parts of the country." |