This article is from the source 'bbc' and was first published or seen on . It last changed over 40 days ago and won't be checked again for changes.

You can find the current article at its original source at https://www.bbc.co.uk/news/health-55659820

The article has changed 72 times. There is an RSS feed of changes available.

Version 58 Version 59
What are the India, Brazil, South Africa and UK variants? What are the Delta, Gamma, Beta and Alpha Covid variants?
(30 days later)
A coronavirus variant, first identified in India, is causing a spike in cases in some parts of the UK and experts are worried. The UK is seeing rising cases of coronavirus caused by a variant called Delta, which was first identified in India.
Experts say this variant, named Delta by the World Health Organization, is more transmissible than even the "Kent" or Alpha variant and is now dominant in the UK. Experts say it is more transmissible than even the "UK/Kent" or Alpha variant which previously dominated here.
It could delay the final stage of easing of England's Covid restrictions on 21 June, although hospitalisations remain flat. Delta is behind almost all new Covid infections.
What is happening with the India variant in the UK? What do we know about Covid variants?
There are a few "India" variants, but one called B.1.617.2 appears to be spreading more quickly in the UK. There are thousands of different variants of Covid circulating across the world. One of them, called Delta or B.1.617.2, appears to be spreading more quickly in some countries, including the UK.
Surge testing is being deployed in some areas, including Bolton and Blackburn, to identify infections - but it may not be stopping the spread.
Second jabs for all over-50s (and the clinically vulnerable) in England are now being brought forward to protect more people, faster. Second doses will come eight weeks after the first, rather than 11-12 weeks.
Latest research suggests the Pfizer and AstraZeneca coronavirus vaccines are highly effective against the variant after two doses, but protection from one dose appears to be reduced.
What do we know about the different variants?
There are thousands of different variants of Covid circulating across the world.
Viruses mutate all the time and most changes are inconsequential. Some even harm the virus. But others can make the disease more infectious or threatening - and these mutations tend to dominate.Viruses mutate all the time and most changes are inconsequential. Some even harm the virus. But others can make the disease more infectious or threatening - and these mutations tend to dominate.
Those with the most potentially concerning changes are called "variants of concern" and kept under the closest watch by health officials, and include: Those with the most potentially concerning changes are called "variants of concern". They are kept under the closest watch by health officials, and include:
The India or Delta variant (B.1.617.2) of which more than 75,000 cases have been seen in across the UK Delta (B.1.617.2) which currently accounts for 99% of new Covid cases in the UK
The UK, Kent or Alpha variant (also known as B.1.1.7) is prevalent in Britain - with more than 200,000 cases identified - and has spread to more than 50 countries and appears to be mutating again Alpha (B.1.1.7), first identified in the UK but which has spread to more than 50 countries and appears to be mutating again
The South Africa or Beta variant (B.1.351) has been identified in at least 20 other countries, including the UK Beta (B.1.351), first identified in South Africa but which has been detected in at least 20 other countries, including the UK
The Brazil or Gamma variant (P.1) has spread to more than 10 other countries, including the UK Gamma (P.1), first identified in Brazil but which has spread to more than 10 other countries, including the UK
Are they more dangerous?Are they more dangerous?
There is no evidence that any of them cause much more serious illness for the vast majority of people.There is no evidence that any of them cause much more serious illness for the vast majority of people.
As with the original version, the risk remains highest for people who are elderly or have significant underlying health conditions.As with the original version, the risk remains highest for people who are elderly or have significant underlying health conditions.
But a virus being more infectious and equally dangerous will in itself lead to more deaths in an unvaccinated population.But a virus being more infectious and equally dangerous will in itself lead to more deaths in an unvaccinated population.
Vaccines offer high protection against severe illness with Covid-19, including infections caused by variants of concern. The shots also reduce the risk of infection. But they are not perfect and do not completely eliminate all risk.
The advice to avoid infection remains the same for all strains: wash your hands, keep your distance, wear a face covering and be vigilant about ventilation.The advice to avoid infection remains the same for all strains: wash your hands, keep your distance, wear a face covering and be vigilant about ventilation.
How many cases are there in the UK?
Why has the Delta variant spread so quickly in UK?
How are the mutants behaving?How are the mutants behaving?
The variants experts concerned about have all undergone changes to their spike protein - the part of the virus which attaches to human cells. The variants of concern have all undergone changes to their spike protein - the part of the virus which attaches to human cells.
The Delta variant has some potentially important ones (such as L452R) that might make it spread more easily. Delta has some potentially important ones (such as L452R) that might make it spread more easily.
There is no evidence to indicate it causes more severe disease or might make current vaccines less effective, say UK officials.There is no evidence to indicate it causes more severe disease or might make current vaccines less effective, say UK officials.
The World Health Organization, meanwhile, has classified another, similar variant that is also circulating in India - called B.1.617 - as a variant of concern. One mutation, called N501Y, shared by the Alpha, Gamma and Beta, seems to make the virus better at infecting cells and spreading.
One mutation, called N501Y, shared by the Alpha, Gamma and Beta variant seems to make the virus better at infecting cells and spreading. Beta and Gamma also have a key mutation, called E484K, that may help the virus sidestep some of the body's immune defences.
The Beta and Gamma variants also have a key mutation, called E484K, that may help the virus evade antibodies, key parts of the immune system which help bodies fight off infection. Experts recently found a small number of cases of Alpha with this change too.
Experts recently found a small number of cases of the Alpha variant that have this change too.
Will vaccines still work against variants?Will vaccines still work against variants?
Current vaccines were designed for earlier versions of coronavirus, but scientists believe they should work, albeit potentially less well. Current vaccines were designed for earlier versions of coronavirus, which means they may not be the ideal match for new variants and so might not work quite as well.
Lab research suggests antibodies that can fight the infection - triggered by vaccination or past infection - may be somewhat less effective against Delta. But experts say they are still very effective at protecting lives by cutting the risk of severe illness:
Two doses of either the Pfizer or AstraZeneca vaccine still protect people from getting very ill, however. An analysis by Public Health England found two doses of either the Pfizer or AstraZeneca vaccine was more than 90% effective against hospitalisations for Covid-19 caused by Delta
Real life data suggest the Pfizer vaccine can protect against the new variants, although slightly less effectively. A single dose, however, was less effective at preventing illness from Delta, compared to how well it worked against Alpha.
Data from the Oxford-AstraZeneca vaccine team suggests it protects just as well against the Alpha variant. It offers less protection against the Beta variant - but should still protect against severe illness. Doctors say it is vital that people get both doses to gain maximum protection against existing and emerging variants.
One recent study suggests the Gamma variant may resist antibodies in people who've recovered from Covid before. How many people have been vaccinated so far?
Some early results suggest the Moderna vaccine is effective against the Beta variant, although the immune response triggered may be weaker and shorter-lived. Which children are being vaccinated and why?
Do variants mean booster jabs are more likely?Do variants mean booster jabs are more likely?
Experts are confident existing vaccines can be redesigned to better tackle emerging mutations.Experts are confident existing vaccines can be redesigned to better tackle emerging mutations.
The UK government has a deal with biopharmaceutical company CureVac to develop vaccines against future variants, and has pre-ordered 50 million doses.The UK government has a deal with biopharmaceutical company CureVac to develop vaccines against future variants, and has pre-ordered 50 million doses.
Depending on how variants continue to develop, these could potentially be used to offer a booster vaccine to older or clinically vulnerable people later in the year.Depending on how variants continue to develop, these could potentially be used to offer a booster vaccine to older or clinically vulnerable people later in the year.
Extra vaccines cash to future-proof UK - ministerExtra vaccines cash to future-proof UK - minister
NHS plans booster jab for those 50 and over before winter