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China’s CanSinoBIO says its vaccine may be less effective over time, but ‘booster shot’ improves its efficacy to over 90% | China’s CanSinoBIO says its vaccine may be less effective over time, but ‘booster shot’ improves its efficacy to over 90% |
(about 2 months later) | |
A single-shot Covid-19 vaccine by CanSino Biologics has shown a decrease in efficacy over time, the manufacturer has said. Getting a “booster shot” six months after the first jab, however, propels its efficacy to over 90%. | A single-shot Covid-19 vaccine by CanSino Biologics has shown a decrease in efficacy over time, the manufacturer has said. Getting a “booster shot” six months after the first jab, however, propels its efficacy to over 90%. |
The Chinese vaccine manufacturer CanSinoBIO provided an update on its vaccine during an online presentation late on Wednesday. Its chief scientific officer, Zhu Tao, said receiving a second jab of the vaccine six months after being inoculated with the single-shot solution had shown promising results during tests. | The Chinese vaccine manufacturer CanSinoBIO provided an update on its vaccine during an online presentation late on Wednesday. Its chief scientific officer, Zhu Tao, said receiving a second jab of the vaccine six months after being inoculated with the single-shot solution had shown promising results during tests. |
“A booster shot six months later led to a seven-times to 10-times increase in neutralizing antibody levels, so we expect in this case efficacy could reach over 90%,” Zhu stated. | “A booster shot six months later led to a seven-times to 10-times increase in neutralizing antibody levels, so we expect in this case efficacy could reach over 90%,” Zhu stated. |
While the first shot’s efficacy may fall over time, it is still believed to be some 50% effective or more five to six months after inoculation. Nonetheless, more clinical trials data is needed in order to provide more precise estimates, Zhu warned. | While the first shot’s efficacy may fall over time, it is still believed to be some 50% effective or more five to six months after inoculation. Nonetheless, more clinical trials data is needed in order to provide more precise estimates, Zhu warned. |
The company published first interim trials data back in February, with the vaccine showing a rather modest efficacy of nearly 69% in preventing asymptomatic Covid-19. Its efficacy then steadily dropped over time, measuring some 65% four weeks after the inoculation. | The company published first interim trials data back in February, with the vaccine showing a rather modest efficacy of nearly 69% in preventing asymptomatic Covid-19. Its efficacy then steadily dropped over time, measuring some 65% four weeks after the inoculation. |
So far, CanSinoBIO’s vaccine has been approved only by a handful of countries, including China, Pakistan, and Mexico. Last week, it also received emergency use approval in Hungary, becoming the second Chinese-made vaccine to be greenlit by the European country. | So far, CanSinoBIO’s vaccine has been approved only by a handful of countries, including China, Pakistan, and Mexico. Last week, it also received emergency use approval in Hungary, becoming the second Chinese-made vaccine to be greenlit by the European country. |
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