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| 'Proof' face creams beat wrinkles | 'Proof' face creams beat wrinkles |
| (10 minutes later) | |
| Scientists say they have clinical proof that a face cream available on the high street does reduce wrinkles. | Scientists say they have clinical proof that a face cream available on the high street does reduce wrinkles. |
| Five months worth of stock of the leading brand sold in a day after Professor Chris Griffiths announced in 2007 it appeared to combat sun damage. | Five months worth of stock of the leading brand sold in a day after Professor Chris Griffiths announced in 2007 it appeared to combat sun damage. |
| Two years on from the BBC Horizon programme showcasing his work, his team has shown the cream visibly smoothes out the skin. | Two years on from the BBC Horizon programme showcasing his work, his team has shown the cream visibly smoothes out the skin. |
| Boots predicts boom sales of its No 7 Protect & Perfect Intense Beauty Serum. | Boots predicts boom sales of its No 7 Protect & Perfect Intense Beauty Serum. |
| This moisturiser is a richer version of its Protect & Perfect Beauty Serum that the team tested before and found it stimulated the production of fibrillin-1, a protein that promotes elasticity in the skin which is lost with sun damage. | This moisturiser is a richer version of its Protect & Perfect Beauty Serum that the team tested before and found it stimulated the production of fibrillin-1, a protein that promotes elasticity in the skin which is lost with sun damage. |
| Approximately one in five people using the cream will get something extra for their money over plain moisturisers Nina Goad of the British Association of Dermatologists | Approximately one in five people using the cream will get something extra for their money over plain moisturisers Nina Goad of the British Association of Dermatologists |
| Although his University of Manchester team only tested one brand of anti-ageing cream, Professor Griffiths said similar products available on the market would probably also work. | Although his University of Manchester team only tested one brand of anti-ageing cream, Professor Griffiths said similar products available on the market would probably also work. |
| In the latest trial, 60 men and women aged 45 to 80 years with typical signs of sun-damaged skin were asked to test one of two products allocated at random so neither the investigators nor volunteers were aware which treatment was given. | In the latest trial, 60 men and women aged 45 to 80 years with typical signs of sun-damaged skin were asked to test one of two products allocated at random so neither the investigators nor volunteers were aware which treatment was given. |
| Half received the Boots cream and half received a moisturiser with none of the "anti-ageing" ingredients - peptides, retinyl palmitate and white lupin extract. | Half received the Boots cream and half received a moisturiser with none of the "anti-ageing" ingredients - peptides, retinyl palmitate and white lupin extract. |
| The volunteers applied the cream each night to the face, wrists and forearms. | The volunteers applied the cream each night to the face, wrists and forearms. |
| As expected, the Boots cream increased fibrillin production. But it also appeared to smooth out wrinkles. | As expected, the Boots cream increased fibrillin production. But it also appeared to smooth out wrinkles. |
| Crow's feet | Crow's feet |
| After six months of daily use, 43% of people using the product were found to have some extra clinical improvement in their wrinkles compared to 22% of people using a basic moisturiser. | After six months of daily use, 43% of people using the product were found to have some extra clinical improvement in their wrinkles compared to 22% of people using a basic moisturiser. |
| This equates to one in five people using the cream having some extra benefit over plain moisturisers. | This equates to one in five people using the cream having some extra benefit over plain moisturisers. |
| At this point in the trial all of the volunteers were told which cream they had been using and were offered the opportunity to continue to take the anti-ageing cream - and all of the treatment group took it. | At this point in the trial all of the volunteers were told which cream they had been using and were offered the opportunity to continue to take the anti-ageing cream - and all of the treatment group took it. |
| The best thing you can do to prevent wrinkles is practice sensible sun avoidance and use sun screen Professor GriffithsUniversity of Manchester | The best thing you can do to prevent wrinkles is practice sensible sun avoidance and use sun screen Professor GriffithsUniversity of Manchester |
| Professor Griffiths said he was surprised by his findings, published in the British Journal of Dermatology, and stressed that they were independent, although the work received funding from Boots. | Professor Griffiths said he was surprised by his findings, published in the British Journal of Dermatology, and stressed that they were independent, although the work received funding from Boots. |
| "We did this in a purely independent way. Either way this paper would have been published otherwise we would have not entered into the study. I suppose Boots were confident or foolhardy, whichever way you want to look at it. | "We did this in a purely independent way. Either way this paper would have been published otherwise we would have not entered into the study. I suppose Boots were confident or foolhardy, whichever way you want to look at it. |
| "Wrinkles are largely down to our exposure to sunlight. The best thing you can do to prevent wrinkles is practice sensible sun avoidance and use sun screen." | "Wrinkles are largely down to our exposure to sunlight. The best thing you can do to prevent wrinkles is practice sensible sun avoidance and use sun screen." |
| And he said prescription creams containing retinoic acid were still better at beating sun damage wrinkles than over-the-counter creams. | And he said prescription creams containing retinoic acid were still better at beating sun damage wrinkles than over-the-counter creams. |
| Nina Goad of the British Association of Dermatologists said: "Approximately one in five people using the cream will get something extra for their money over plain moisturisers. | Nina Goad of the British Association of Dermatologists said: "Approximately one in five people using the cream will get something extra for their money over plain moisturisers. |
| "It is an interesting step forward in research although the long term benefits are unknown. | "It is an interesting step forward in research although the long term benefits are unknown. |
| "The main preventable causes of skin ageing are sun exposure and smoking, so if you're worried about wrinkles, limiting these factors is sensible." | "The main preventable causes of skin ageing are sun exposure and smoking, so if you're worried about wrinkles, limiting these factors is sensible." |
| Dr Nick Lowe, clinical professor of dermatology at UCLA School of Medicine, said: "The previous rapid study reported from this group measured fibrillin a substance that predicts the formulation of collagen. More collagen should result in skin rejuvenation. | Dr Nick Lowe, clinical professor of dermatology at UCLA School of Medicine, said: "The previous rapid study reported from this group measured fibrillin a substance that predicts the formulation of collagen. More collagen should result in skin rejuvenation. |
| "This latest longer study over six months appears to confirm skin rejuvenation as measured by dermatology examination." | "This latest longer study over six months appears to confirm skin rejuvenation as measured by dermatology examination." |
| Dr Richard Weller, senior lecturer in dermatology at the University of Edinburgh, said: "This is, as far as I am aware, the first properly conducted placebo controlled, double blind trial of an over the counter cosmetic product. Boots are to be congratulated for doing this. | |
| "This will raise the bar for what we should expect from the cosmetic companies in showing that their products work." | |
| No7 Protect & Perfect Intense Beauty Serum is the new name for No7 Refine & Rewind Beauty Serum. | No7 Protect & Perfect Intense Beauty Serum is the new name for No7 Refine & Rewind Beauty Serum. |