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| World’s first plasmid DNA vaccine against Covid-19 gets emergency approval in India | World’s first plasmid DNA vaccine against Covid-19 gets emergency approval in India |
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| India’s drug regulator has approved a three-dose Covid-19 vaccine which uses plasmid DNA technology developed by indigenous drugmaker Zydus Cadila, after trials indicated it was 66.6% effective. | India’s drug regulator has approved a three-dose Covid-19 vaccine which uses plasmid DNA technology developed by indigenous drugmaker Zydus Cadila, after trials indicated it was 66.6% effective. |
| On Friday, the Drug Controller General of India gave the green light to Zydus Cadila’s Covid-19 vaccine. The inoculation, now the sixth such to be approved in India, has received Emergency Use Authorization (EUA) for use in adults and children aged 12 and above. | On Friday, the Drug Controller General of India gave the green light to Zydus Cadila’s Covid-19 vaccine. The inoculation, now the sixth such to be approved in India, has received Emergency Use Authorization (EUA) for use in adults and children aged 12 and above. |
| The generic drugmaker, which applied for authorization of its three-dose vaccine in July, enlisted 28,000 volunteers into its trial. Data from the late-stage trial suggested the jab was 66.6% effective at preventing symptomatic Covid-19. | The generic drugmaker, which applied for authorization of its three-dose vaccine in July, enlisted 28,000 volunteers into its trial. Data from the late-stage trial suggested the jab was 66.6% effective at preventing symptomatic Covid-19. |
| The vaccine, known as ZyCoV-D, is the world’s first vaccine against Covid-19 that uses plasmid DNA technology. It works by injecting genetically-engineered plasmid containing the DNA sequence of the pathogen. | The vaccine, known as ZyCoV-D, is the world’s first vaccine against Covid-19 that uses plasmid DNA technology. It works by injecting genetically-engineered plasmid containing the DNA sequence of the pathogen. |
| Cadila’s vaccine was developed in partnership with India’s Department of Biotechnology and is the second home-grown shot to be approved for use against Covid-19; the first being Bharat Biotech’s Covaxin jab. | Cadila’s vaccine was developed in partnership with India’s Department of Biotechnology and is the second home-grown shot to be approved for use against Covid-19; the first being Bharat Biotech’s Covaxin jab. |
| Instead of traditional syringes, the vaccine is administered using a needle-free applicator. The system delivers medicine to intramuscular and subcutaneous tissue depths without needles, which may prove particularly useful in a world competing for needles and syringes. | Instead of traditional syringes, the vaccine is administered using a needle-free applicator. The system delivers medicine to intramuscular and subcutaneous tissue depths without needles, which may prove particularly useful in a world competing for needles and syringes. |
| Cadila has already started stockpiling its vaccine and hopes to make 100 million to 120 million doses every year, enough for 40 million people, the company’s managing director told Reuters in April. | Cadila has already started stockpiling its vaccine and hopes to make 100 million to 120 million doses every year, enough for 40 million people, the company’s managing director told Reuters in April. |
| Despite being one of the world’s largest vaccine manufacturers, India’s Covid-19 inoculation program has fallen flat amid a shortage of shots. Delhi has been pushing for ‘Atmanirbhar Bharat’, a Hindi phrase roughly translating as ‘self-reliant India’, in a number of fields, including defense technology and medical products. The vaccination program was meant to reflect India’s self-reliance and burgeoning manufacturing capacity in the medical and pharmaceutical industry. | Despite being one of the world’s largest vaccine manufacturers, India’s Covid-19 inoculation program has fallen flat amid a shortage of shots. Delhi has been pushing for ‘Atmanirbhar Bharat’, a Hindi phrase roughly translating as ‘self-reliant India’, in a number of fields, including defense technology and medical products. The vaccination program was meant to reflect India’s self-reliance and burgeoning manufacturing capacity in the medical and pharmaceutical industry. |
| As the Delta variant caused a surge in cases earlier in 2021, Delhi moved to prevent the export of vaccines, redirecting shipments for Indian needs. | As the Delta variant caused a surge in cases earlier in 2021, Delhi moved to prevent the export of vaccines, redirecting shipments for Indian needs. |
| If you like this story, share it with a friend! | If you like this story, share it with a friend! |