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Q&A: E. coli outbreak Q&A: E. coli outbreak
(40 minutes later)
By Helen Briggs Health editor, BBC News websiteBy Helen Briggs Health editor, BBC News website
An outbreak of E. coli linked to contaminated salad vegetables has caused at least 13 deaths and hundreds of infections in Germany, Sweden and other countries.An outbreak of E. coli linked to contaminated salad vegetables has caused at least 13 deaths and hundreds of infections in Germany, Sweden and other countries.
What is E coli?What is E coli?
E. coli is short for Escherichia coli. It is a type of bacteria present in the gut of humans and other animals. Most strains are harmless but some are able to produce toxins that can cause symptoms such as severe cramps and diarrhoea.E. coli is short for Escherichia coli. It is a type of bacteria present in the gut of humans and other animals. Most strains are harmless but some are able to produce toxins that can cause symptoms such as severe cramps and diarrhoea.
What do we know about this outbreak?What do we know about this outbreak?
The World Health Organization says the E. coli is a completely new strain of bacteria.The World Health Organization says the E. coli is a completely new strain of bacteria.
Researchers in Germany say preliminary genetic analysis of the outbreak suggests the bacteria is unique Researchers in China say preliminary genetic analysis of the outbreak suggests the bacteria is unique
They say it has genes from two distinct groups of E. coli: enteroaggregative E. coli (EAEC) and enterohemorrhagic E. coli (EHEC).They say it has genes from two distinct groups of E. coli: enteroaggregative E. coli (EAEC) and enterohemorrhagic E. coli (EHEC).
Previously authorities had suspected strain O104, which is rare.Previously authorities had suspected strain O104, which is rare.
What are the health effects?What are the health effects?
The outbreak is causing severe infections and in a number of cases, affecting the blood and kidneys.The outbreak is causing severe infections and in a number of cases, affecting the blood and kidneys.
Haemolytic uraemic syndrome - an unusual complication of some types of E. coli as well as other infections - has been seen in hundreds of current cases.Haemolytic uraemic syndrome - an unusual complication of some types of E. coli as well as other infections - has been seen in hundreds of current cases.
Symptoms include bloody diarrhoea and fevers. Epileptic fits can occur in severe cases.Symptoms include bloody diarrhoea and fevers. Epileptic fits can occur in severe cases.
Haemolytic uraemic syndrome can be fatal and can sometimes lead to chronic kidney problems in later life.Haemolytic uraemic syndrome can be fatal and can sometimes lead to chronic kidney problems in later life.
What is the health advice?What is the health advice?
The exact source of the contamination has not yet been determined.The exact source of the contamination has not yet been determined.
Until the cause is known, German officials are telling people to avoid eating raw tomatoes, cucumbers and leafy salad including lettuce, especially in the north of the country, until further notice.Until the cause is known, German officials are telling people to avoid eating raw tomatoes, cucumbers and leafy salad including lettuce, especially in the north of the country, until further notice.
The UK's Health Protection Agency recommends travellers follow the same advice.The UK's Health Protection Agency recommends travellers follow the same advice.
It says anyone returning from Germany with illness including bloody diarrhoea should seek urgent medical attention and mention their travel history.It says anyone returning from Germany with illness including bloody diarrhoea should seek urgent medical attention and mention their travel history.
There have been seven cases in the UK.There have been seven cases in the UK.
The Food Standards Agency in the UK has issued general advice on the need to wash fruit and vegetables.The Food Standards Agency in the UK has issued general advice on the need to wash fruit and vegetables.
The agency says: "It's a good idea to wash fruit and vegetables before you eat them to ensure that they are clean, and to help remove germs that might be on the outside.The agency says: "It's a good idea to wash fruit and vegetables before you eat them to ensure that they are clean, and to help remove germs that might be on the outside.
"Peeling or cooking fruit and vegetables can also remove these germs.""Peeling or cooking fruit and vegetables can also remove these germs."
However, a Scottish expert said new research suggests washing alone may not be enough, as the bacteria may be inside the food.However, a Scottish expert said new research suggests washing alone may not be enough, as the bacteria may be inside the food.
Dr Nicola Holden of The James Hutton Institute said: "The bacteria are able to get from animal sources on to crops through different routes, most likely in irrigation water or sometimes from slurry spraying, while some contamination can also occur during processing and packaging."Dr Nicola Holden of The James Hutton Institute said: "The bacteria are able to get from animal sources on to crops through different routes, most likely in irrigation water or sometimes from slurry spraying, while some contamination can also occur during processing and packaging."
She said the bacteria can colonise plant roots, moving up to the edible foliage or fruits.She said the bacteria can colonise plant roots, moving up to the edible foliage or fruits.
"The threat to human health occurs because these bacteria are not simply sitting on the surface of the plant and are particularly difficult to remove post-harvest," she added."The threat to human health occurs because these bacteria are not simply sitting on the surface of the plant and are particularly difficult to remove post-harvest," she added.
What do other experts say?What do other experts say?
Professor Brendan Wren from the London School of Hygiene & Tropical Medicine said E. coli can attach to the surface of fresh produce such as lettuce leaves, spinach leaves and cucumber.Professor Brendan Wren from the London School of Hygiene & Tropical Medicine said E. coli can attach to the surface of fresh produce such as lettuce leaves, spinach leaves and cucumber.
"These types of E.coli survive harsher environmental conditions than the typical E. coli and produce some nasty toxins to humans," he said."These types of E.coli survive harsher environmental conditions than the typical E. coli and produce some nasty toxins to humans," he said.
"They can survive in soil environments and fertiliser may be one source for the origin of the outbreak related to fresh produce such as cucumbers.""They can survive in soil environments and fertiliser may be one source for the origin of the outbreak related to fresh produce such as cucumbers."
Dr Jonathan Fletcher, senior lecturer in microbiology at the University of Bradford, said toxin-producing E. coli can cause very serious disease in humans, especially in the elderly or very young.Dr Jonathan Fletcher, senior lecturer in microbiology at the University of Bradford, said toxin-producing E. coli can cause very serious disease in humans, especially in the elderly or very young.
Cattle seem to carry the toxin in their gut, without showing signs of illness, and it will be shed in the faeces.Cattle seem to carry the toxin in their gut, without showing signs of illness, and it will be shed in the faeces.
"If cattle manure is used as a fertiliser, it is probable that vegetables such as cucumbers will be contaminated with E. coli, and if not washed properly it would be present in sufficient numbers to cause the infection.""If cattle manure is used as a fertiliser, it is probable that vegetables such as cucumbers will be contaminated with E. coli, and if not washed properly it would be present in sufficient numbers to cause the infection."
Where has it come from?Where has it come from?
The source of this outbreak is believed to be contaminated salad vegetables.The source of this outbreak is believed to be contaminated salad vegetables.
Initial reports that cucumbers were the source of the bacteria have not been confirmed and other food sources are being sampled.Initial reports that cucumbers were the source of the bacteria have not been confirmed and other food sources are being sampled.
While E. coli infection is often caused by eating undercooked meat and eggs, there has been a recent rise in cases caused by fresh fruit and vegetables.While E. coli infection is often caused by eating undercooked meat and eggs, there has been a recent rise in cases caused by fresh fruit and vegetables.
They include foods that are eaten raw or only lightly cooked, such as salads, fresh fruit and bean sprouts.They include foods that are eaten raw or only lightly cooked, such as salads, fresh fruit and bean sprouts.
A whole host of foods have been linked with past E. coli outbreaks.A whole host of foods have been linked with past E. coli outbreaks.
What about the UK?What about the UK?
The total number of cases in the UK is seven.The total number of cases in the UK is seven.
That includes three British nationals and four Germans. It seems all picked up the infection in Germany.That includes three British nationals and four Germans. It seems all picked up the infection in Germany.
Three have developed the potentially deadly complication of haemolytic uraemic syndrome.Three have developed the potentially deadly complication of haemolytic uraemic syndrome.