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Daily aspirin 'risky' for healthy | Daily aspirin 'risky' for healthy |
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Healthy people should not take aspirin to ward off heart attacks and cancer, according to the most comprehensive review of the risks and benefits. | Healthy people should not take aspirin to ward off heart attacks and cancer, according to the most comprehensive review of the risks and benefits. |
There has been growing debate about whether all people over 50 should take a daily, low dose aspirin. | There has been growing debate about whether all people over 50 should take a daily, low dose aspirin. |
But the review, conducted by the research arm of the NHS, said it was a "fine balance" due to the dangers of bleeding in the brain and stomach. | But the review, conducted by the research arm of the NHS, said it was a "fine balance" due to the dangers of bleeding in the brain and stomach. |
Overall it warned against taking the drug, until there was more evidence. | Overall it warned against taking the drug, until there was more evidence. |
Aspirin makes the blood less sticky so it reduces the odds of a blood clot forming inside the body, which could cause a heart attack or stroke. | Aspirin makes the blood less sticky so it reduces the odds of a blood clot forming inside the body, which could cause a heart attack or stroke. |
There are even studies suggesting it can cut the risk of some cancers. | There are even studies suggesting it can cut the risk of some cancers. |
However, as the drug makes it harder for the blood to clot it can cause problems inside the body. | However, as the drug makes it harder for the blood to clot it can cause problems inside the body. |
The drug is given to people at high risk of a heart attack or stroke as the medical benefit is clear. | The drug is given to people at high risk of a heart attack or stroke as the medical benefit is clear. |
However, there have been calls to give aspirin to otherwise healthy people as well. | However, there have been calls to give aspirin to otherwise healthy people as well. |
A team at Warwick Medical School was asked to assess the evidence by the NHS National Institute for Health Research. | A team at Warwick Medical School was asked to assess the evidence by the NHS National Institute for Health Research. |
For heart attacks and strokes, they concluded giving everyone aspirin would cause "net harm due to increased potential for bleeding". | For heart attacks and strokes, they concluded giving everyone aspirin would cause "net harm due to increased potential for bleeding". |
This was in part due to better management of at-risk patients including prescribing drugs to lower blood pressure. | This was in part due to better management of at-risk patients including prescribing drugs to lower blood pressure. |
On cancer, they concluded the evidence was not strong enough to base a decision on, but trials taking place would give clearer proof in the next five years. | On cancer, they concluded the evidence was not strong enough to base a decision on, but trials taking place would give clearer proof in the next five years. |
Prof Aileen Clarke, who led the review, told the BBC: "The risks are finely balanced and for now there is not the evidence to advise people to take it. | Prof Aileen Clarke, who led the review, told the BBC: "The risks are finely balanced and for now there is not the evidence to advise people to take it. |
"It would be lovely to say over-50s should take an aspirin a day and have much less cancer, but the research hasn't yet been done and we should be cautious. | "It would be lovely to say over-50s should take an aspirin a day and have much less cancer, but the research hasn't yet been done and we should be cautious. |
"We need to be extremely careful about over-promoting aspirin." | "We need to be extremely careful about over-promoting aspirin." |
Amy Thompson, senior cardiac nurse at the British Heart Foundation, said: "Aspirin is extremely important for many heart patients, but for people free of heart disease the jury is still out as the risks are likely to outweigh the benefits. | |
"Further research is underway which will shed light on who else is likely to benefit the most from taking aspirin." |
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