This article is from the source 'guardian' and was first published or seen on . It last changed over 40 days ago and won't be checked again for changes.

You can find the current article at its original source at http://www.theguardian.com/society/2014/sep/24/expanding-waistline-women-predictor-breast-cancer-risk-ucl

The article has changed 2 times. There is an RSS feed of changes available.

Version 0 Version 1
Expanding waistline for women ‘is a predictor for breast cancer risk’ Expanding waistline for women ‘is a predictor for breast cancer risk’
(35 minutes later)
Women who go up a skirt size every 10 years between their mid-20s and mid-60s are at 33% greater risk of developing breast cancer after the menopause, a study of more than 90,000 women finds.Women who go up a skirt size every 10 years between their mid-20s and mid-60s are at 33% greater risk of developing breast cancer after the menopause, a study of more than 90,000 women finds.
Overall weight gain, usually measured through an increase in BMI (body mass index), was already known to be a risk factor but the study, believed to be the first to look at the association between change in skirt size and breast cancer, indicates that a thickening of the waist could be particularly harmful. Overall weight gain, usually measured through an increase in BMI (body mass index), was known to be a risk factor but the study, believed to be the first to look at the association between change in skirt size and breast cancer, indicates that a thickening of the waist could be particularly harmful.
The researchers, from the department of women’s cancer at UCL, believe the results, which also showed going up two skirt sizes every 10 years over the same period was associated with a 77% greater risk, could be valuable in breast cancer prevention. The researchers, from the Ddepartment of women’s cancer at UCLUniversity College London, believe the results, which also showed going up two skirt sizes every 10 years over the same period was associated with a 77% greater risk, could be valuable in breast cancer prevention.
Usha Menon, a co-author of the report, said: “Given that obesity is now emerging as a global epidemic, from a public health prospective our findings are significant as they provide women with a simple and easy to understand message. It needs effort to calculate the BMI from height and weight and most of us do not remember what it might have been some years ago. In that respect, skirt size as a proxy for waist circumference is easily remembered over time.” Usha Menon, a co-author of the report, said: “Given that obesity is now emerging as a global epidemic, from a public health prospective our findings are significant as they provide women with a simple and easy to understand message. It needs effort to calculate the BMI from height and weight and most of us do not remember what it might have been some years ago. In that respect, skirt size as a proxy for waist circumference is easily remembered over time.”
The researchers estimate that the five-year absolute risk of postmenopausal breast cancer rises from one in 61 to one in 51 with each increase in skirt size every 10 years. Adding BMI did not significantly improve the prediction of risk in the study, which is published in BMJ Open.The researchers estimate that the five-year absolute risk of postmenopausal breast cancer rises from one in 61 to one in 51 with each increase in skirt size every 10 years. Adding BMI did not significantly improve the prediction of risk in the study, which is published in BMJ Open.
The researchers questioned 92,834 women over 50, taking part in the UK Collaborative Trial of Ovarian Cancer Screening and not known to have breast cancer, about their current and past skirt sizes. The researchers questioned 92,834 women over 50, taking part in a cancer screening trialthe UK Collaborative Trial of Ovarian Cancer Screening and not known to have breast cancer, about their current and past skirt sizes.
At the age of 25, the women’s average size had been a UK 12 (US 8, Europe 40-44) and when they entered the study, at the average age of 64, it was a 14 (US: 10, Europe 42-46). As it was an observational study definitive conclusions could not be drawn about cause and effect.At the age of 25, the women’s average size had been a UK 12 (US 8, Europe 40-44) and when they entered the study, at the average age of 64, it was a 14 (US: 10, Europe 42-46). As it was an observational study definitive conclusions could not be drawn about cause and effect.
The researchers said their findings required validation by others but pointed out that an expanding waistline had been linked to other cancers, including those of the pancreas, lining of the womb, and ovaries, possibly because midriff fat was more harmful.The researchers said their findings required validation by others but pointed out that an expanding waistline had been linked to other cancers, including those of the pancreas, lining of the womb, and ovaries, possibly because midriff fat was more harmful.
During the monitoring period, 1,090 women developed breast cancer. As expected, infertility treatment, family history of breast or ovarian cancer, and hormone replacement therapy, were all significantly associated with a heightened risk.
But increases in skirt size emerged as the strongest predictor of risk with a stronger association than absolute skirt size.
However, Tom Stansfeld, Cancer Research UK’s health information officer, questioned the reliability of the findings, citing limitations raised by the authors themselves. “This study relied on women remembering what size they were at least 30 years ago which could be unreliable. Also, dress sizes have changed over the years so it’s hard to be sure what each size really means. Evidence tells us the most important things you can do to reduce breast cancer risk, especially after the menopause, is to keep to a healthy weight, be physically active as often as you can, and cut down on alcohol.”