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Genital warts: NHS 'must vaccinate' Genital warts: NHS 'must vaccinate'
(40 minutes later)
VIEWPOINT By Dr Colm O'Mahony and Dr Steve Taylor Chester Foundation Trust Hospital and Birmingham Heartlands HospitalVIEWPOINT By Dr Colm O'Mahony and Dr Steve Taylor Chester Foundation Trust Hospital and Birmingham Heartlands Hospital
The NHS vaccinates teenage girls against cervical cancer with the Cervarix vaccine. It offers good protection, but does not also protect against genital warts.The NHS vaccinates teenage girls against cervical cancer with the Cervarix vaccine. It offers good protection, but does not also protect against genital warts.
In this week's Scrubbing Up, two sexual health experts argue that if the vaccine used was changed to Gardisal, teenagers would also get protection from genital warts.In this week's Scrubbing Up, two sexual health experts argue that if the vaccine used was changed to Gardisal, teenagers would also get protection from genital warts.
Genital warts are just a cosmetic nuisance, right?Genital warts are just a cosmetic nuisance, right?
You try telling that to somebody who has just discovered a load of unpleasant 'mini-cauliflowers' in the genital area.You try telling that to somebody who has just discovered a load of unpleasant 'mini-cauliflowers' in the genital area.
In our long careers as sexual health consultants we can safely say that the patients who discover genital warts are some of the most distressed and upset patients we have ever met. At 135,000 new and recurrent cases per year, it is the commonest sexually transmitted infection dealt with in our clinics.In our long careers as sexual health consultants we can safely say that the patients who discover genital warts are some of the most distressed and upset patients we have ever met. At 135,000 new and recurrent cases per year, it is the commonest sexually transmitted infection dealt with in our clinics.
Imagine our delight then when in 2007 it was announced that there was a vaccine available for the Human Papilloma Virus (HPV) - the virus responsible for genital warts and the government was considering a national vaccination programme.Imagine our delight then when in 2007 it was announced that there was a vaccine available for the Human Papilloma Virus (HPV) - the virus responsible for genital warts and the government was considering a national vaccination programme.
Saving money?Saving money?
Unfortunately, there were two vaccines, one which did not cover the genital warts virus at all - Cervarix - and a second vaccine - Gardasil - which covered the viruses that cause cervical cancer, HPV 16 and 18, but also types six and 11 which cause almost 100% of all genital warts in the UK.Unfortunately, there were two vaccines, one which did not cover the genital warts virus at all - Cervarix - and a second vaccine - Gardasil - which covered the viruses that cause cervical cancer, HPV 16 and 18, but also types six and 11 which cause almost 100% of all genital warts in the UK.
We naively thought at the time this was no contest, genital warts cost millions of pounds, as not only do types six and 11 cause warts but they also cause thousands of cervical smears to be classified as abnormal resulting in thousands of visits to GPs, gynaecology departments and sexual health clinics for wart treatments.We naively thought at the time this was no contest, genital warts cost millions of pounds, as not only do types six and 11 cause warts but they also cause thousands of cervical smears to be classified as abnormal resulting in thousands of visits to GPs, gynaecology departments and sexual health clinics for wart treatments.
The Joint Vaccination Committee recommended HPV vaccination and said that if the vaccines were the same price, Gardasil should be chosen but if Cervarix was considerably cheaper then it might be the option.The Joint Vaccination Committee recommended HPV vaccination and said that if the vaccines were the same price, Gardasil should be chosen but if Cervarix was considerably cheaper then it might be the option.
The reduction in cervical cancers wouldn't be seen until 2025 whereas in a year of the vaccine programme with Gardasil we would have started to see a reduction in genital warts and started saving millions of pounds not to mention reduction in workload and distressed patients.The reduction in cervical cancers wouldn't be seen until 2025 whereas in a year of the vaccine programme with Gardasil we would have started to see a reduction in genital warts and started saving millions of pounds not to mention reduction in workload and distressed patients.
Gardasil for our childrenGardasil for our children
It's extraordinary that we are the only developed country in the world, apart from Holland, to have chosen Cervarix for the national programme. The Republic of Ireland did the maths and chose Gardasil.It's extraordinary that we are the only developed country in the world, apart from Holland, to have chosen Cervarix for the national programme. The Republic of Ireland did the maths and chose Gardasil.
Australia, which was first country out of the blocks, had a vaccination programme for young women between the ages of 12-26 and within the year of their Gardasil vaccine programme finishing, were already seeing a 47% reduction in genital wart presentation in young women with a corresponding 17% reduction in young men from herd immunity.Australia, which was first country out of the blocks, had a vaccination programme for young women between the ages of 12-26 and within the year of their Gardasil vaccine programme finishing, were already seeing a 47% reduction in genital wart presentation in young women with a corresponding 17% reduction in young men from herd immunity.
A recent Australian study calculated that the only 'danger to Australia in the future would be unvaccinated backpackers' - Brits.A recent Australian study calculated that the only 'danger to Australia in the future would be unvaccinated backpackers' - Brits.
We, as consultants in sexual health, have been told to say nothing publicly that would damage the current vaccine programme as the Cervarix vaccine has already been purchased. We have had to be circumspect in public but in private we have all purchased Gardasil for our own children and advised colleagues to do the same.We, as consultants in sexual health, have been told to say nothing publicly that would damage the current vaccine programme as the Cervarix vaccine has already been purchased. We have had to be circumspect in public but in private we have all purchased Gardasil for our own children and advised colleagues to do the same.
'Horse has bolted''Horse has bolted'
It is sad that a golden opportunity to eradicate the commonest sexually transmitted infection in the UK, has been ignored. This decision will be regretted for many years to come. A small chink of light is the fact that the contract is up for renewal this year.It is sad that a golden opportunity to eradicate the commonest sexually transmitted infection in the UK, has been ignored. This decision will be regretted for many years to come. A small chink of light is the fact that the contract is up for renewal this year.
However, this will only now involve 13-year-olds as the horse has already bolted, with all 13 to 18-year-old girls already vaccinated with Cervarix.However, this will only now involve 13-year-olds as the horse has already bolted, with all 13 to 18-year-old girls already vaccinated with Cervarix.
Common sense and economics dictate that the decision to change and use Gardasil needs to be made sooner rather than later.Common sense and economics dictate that the decision to change and use Gardasil needs to be made sooner rather than later.
There are those that say 'So what, genital warts are a punishment for promiscuous behaviour' - that is callous and unfair - even skin contact is enough to transmit HPV; condoms do not prevent transmission or acquisition of HPV so even young women who try to be careful are at risk from this virus.There are those that say 'So what, genital warts are a punishment for promiscuous behaviour' - that is callous and unfair - even skin contact is enough to transmit HPV; condoms do not prevent transmission or acquisition of HPV so even young women who try to be careful are at risk from this virus.
In our clinics we can only apologise to any young women we see who has had her full three doses of Cervarix and yet presents in great distress with genital warts. This was a bad decision, let's hope the new government will make a re-assessment, taking all the economic and social factors into consideration and reverse this decision.In our clinics we can only apologise to any young women we see who has had her full three doses of Cervarix and yet presents in great distress with genital warts. This was a bad decision, let's hope the new government will make a re-assessment, taking all the economic and social factors into consideration and reverse this decision.
Neither author has any financial interest in either Cervarix or GardasilNeither author has any financial interest in either Cervarix or Gardasil


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@F - Fon't disagree that the decision should be reviewed. If true then Gardasil should never have been chosen. But the fact that GSK is British is not unimportant - you'll find employers pay a lot of NI too. Contrast Pfizer's closure of UK R&D with the loss 2,400 science-base jobs with GSK's recent investments. No R&D = no value = no tax = no NHS = no jobs for doctors, nurse & drugs.
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  • @norwici If you factor in cost savings pertaining to genital warts, Gardasil actually works out more cost effective than Cervarix. It did at the time of the first contract and still does.Individuals in the UK pay National Insurance towards the NHS and in return expect to have the NHS deliver the best it can (within its financial constraints). Political decisions should not impact public health@norwici If you factor in cost savings pertaining to genital warts, Gardasil actually works out more cost effective than Cervarix. It did at the time of the first contract and still does.Individuals in the UK pay National Insurance towards the NHS and in return expect to have the NHS deliver the best it can (within its financial constraints). Political decisions should not impact public health
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  • @paba1- If you speak to any public health clinician, they will tell you the two greatest steps forward in improving the health of the population are clean water ( you can include sanitation in this if you wish) and vaccination. Improved nutrition does not prevent infection. Improved nutrition does not eradicate disease ( eg smallpox). That is down to vaccination.@paba1- If you speak to any public health clinician, they will tell you the two greatest steps forward in improving the health of the population are clean water ( you can include sanitation in this if you wish) and vaccination. Improved nutrition does not prevent infection. Improved nutrition does not eradicate disease ( eg smallpox). That is down to vaccination.
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  • Just one example of the many concerns from USA.http://voices.washingtonpost.com/virginiapolitics/2011/01/house_approves_bill_to_end_hpv.htmlJust one example of the many concerns from USA.http://voices.washingtonpost.com/virginiapolitics/2011/01/house_approves_bill_to_end_hpv.html
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  • 1. Gardasil is much more expensive than Cervarix. If the saved money can save or improve more lives than Gardasil would, Cervarix is the right decision, if we do not have infinite resources for the NHS (which we don't).2. GSK is a UK company paying UK tax which funds the NHS. Merck is not.The government wasn't wrong to choose Cervarix, but that doesn't mean the decision should not be reviewed.1. Gardasil is much more expensive than Cervarix. If the saved money can save or improve more lives than Gardasil would, Cervarix is the right decision, if we do not have infinite resources for the NHS (which we don't).2. GSK is a UK company paying UK tax which funds the NHS. Merck is not.The government wasn't wrong to choose Cervarix, but that doesn't mean the decision should not be reviewed.
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  • Dear F, the major impacts on health have been through better sanitation and nutritrion. Ipso facto a number of those diseases mentioned were already on the decline as a result of better sanitation prior to the implementation of vaccines. Drug companies make huge profits out of creating new markets for vaccines and are protected from prosecution.
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